It's poker night at Princeton Plainsboro when the hospital hosts an oncology benefit. A 6-year-old boy is brought in exhibiting symptoms that aren't too unusual; however, when House learns of additional specifics, he jumps on the case right away. He's seen this set of unique symptoms before - in a previous case when an elderly patient lost her life. House is convinced the boy's case is identical and that he can predict the course of the young patient's illness. Relying on Wilson to stall Cuddy at the poker table so she stays out of his way on this one, House becomes increasingly frustrated and desperate to stop the young boy's illness from progressing, in order to prevent him from suffering the same fate as the former patient.

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