In pursuit of Marisol's killer, Horatio and Delko go to Brazil to avenge her death.

In Rio, Horatio and Delko are close to catching Riaz, Marisol's killer. There, Horatio reunites with Yelina and learns that his brother Raymond is in too deep undercover in a drug ring run by Riaz. To make matters worse, Horatio's nephew, Ray Jr., is working as a drug mule for Riaz, smuggling drugs into the U.S. Now, with the stakes set high, Horatio must catch Riaz before he takes the life of another member of Horatio's family.

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