Nick and Keppler's case leads them to uncover a black market for human body parts while the rest of the CSI team investigates the case of a wealthy married woman who was found murdered in her own home.

A case involving a man's torched corpse, whose bones and tissues had been harvested, leads Nick and Keppler into the disturbing world of illegally secured and sold human body parts. Meanwhile, Warrick and Sara learn more than they care for about the workings of a new-concept "host club" for women, after discovering that the reportedly happily married murdered woman had been pursuing a "relationship" with Jesse, one of the establishment's most handsome and popular young hosts.

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