When a devastating car accident leaves Jaime Sommers (Michelle Ryan) at death's door, her only hope of survival is a cutting-edge, top-secret technology performed by her boyfriend, Dr. Will Anthros (Chris Bowers), and with her new bionics come a covert life that she is not sure she is ready to lead. Meanwhile, the first bionic woman Sarah Corvus (guest star Katee Sackhoff), has her own agenda as she tracks Jaime and Will down - which leads to a showdown between the two bionic woman. Also, Will's father, Dr. Anthony Anthros (Mark Sheppard) escapes from a maximum security prison.