When a teen wrestler comes in the ER with severe vomiting, Pratt (Mekhi Phifer) quickly tries to solve the problem only to find out that the cause is much more serious. While working in the ICU, Gates (John Stamos) tries to help a young kid with a deadly disease. Meanwhile, Abby (Maura Tierney) and Morris (Scott Grimes) jump in to save two volunteer cops brought in with gunshot wounds.