Susan is miffed when Mike's unexpected - and very sexy - houseguest (guest-star Heather Stephens) Kendra forces him to postpone their first official "date." Susan and Edie decide to follow him and Kendra on their night out together. Lynette becomes steadily more dependent on the twins' ADD medication. Gabrielle becomes jealous of the "other" woman, Danielle Van De Kamp in John's life. Meanwhile, Bree's kids mutiny when they learn their dad has moved out. Tom is not happy when Lynette tries to take over his concept of new "Spotless Scrubs" to his clients.

A man has a heartattack while jogging and lands on Mrs. Huber's (guest-star Christine Estabrook) lawn, but she dumps him on Bree's lawn so that she'll call the paramedics and they will ruin her lawn instead of hers. Andrew gets into a serious car accident that puts Mama Solis (guest-star Lupe Ontiveros) in the hospital, right after she finally bust Gabrielle and John having their affair in Carlos' house. Bree and Rex are also called to Andrew's school after he shoves a kid into a locker. Bree learns Rex is serving her with divorce papers. Lastly, the enigmatic Mr. Shaw (guest-star Richard Roundtree) comes closer to solving one of Wisteria Lane's big mysteries.

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