Susan and Mike decide to move in together, much to Edie's displeasure, who schemes against them using Susan's friends. Meanwhile, Lynette takes steps to make sure Annabel (guest-star Melinda McGraw) doesn't come between her and Tom, and the consequences land Tom out of work. Bree comes to a realization about her "buddy" George the pharmacist (guest-star Roger Bart), who continues to interfere in her and Rex's lives. Rex has another heart attack, though prior to it, it seems George has permanently put in a wrench in Bree and Rex's relationship. Carlos' legal problems take a turn for the worse, when Gabrielle decides to leave him after discovering the truth about the birth control. Carlos' subsequent actions increases his jail time to eight years. Mike goes after Paul thanks to Felicia, and Susan goes after Mike, though she doesn't find him. Mrs. Huber's journal reveals some secrets. Lastly, two new faces arrive on Wisteria Lane.

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