Kalvin, a gay man with full-blown AIDS, confronts House in front of his home, demands that House figure out what's causing his illness - besides HIV or AIDS - and collapses at his feet. When Kalvin claims that House assaulted him, Cuddy tells House to give Stacy the facts. House meets with Stacy at her home - armed with some unethically-garnered personal information about her - and he and Stacy share close quarters when he tries to help her exterminate a mouse from her attic, to the chagrin of her temporarily handicapped husband, Mark. During an exam, Kalvin accidentally coughs HIV-positive blood onto Cameron's face, and she is forced to confront the possibility that her life may be changed forever. When House discovers Kalvin's father is suffering from unique symptoms of his own, he must figure out if they are connected and solve the puzzle to save both father and son.

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