| Plot |
| 4x01 - Chapter Sixty-Seven: |
| Ronnie witnesses an attempted rape, then receives a shock when she presses for legal action on behalf of the victim (guest star Amanda Fuller); Hanson tries to prevent a student from being expelled for drugs. |
| 4x02 - Chapter Sixty-Nine: |
| After a cheerleader is attacked, blame falls on another student's mother (Sean Young); Carmen goes head to head with a "bad boy" student (Milo Ventigmilia); Hansen copes with a student who says he is the son of God. |
| 4x03 - Chapter Sixty-Eight: |
| A female student files a serious sexual-harassment charge against Danny; a classroom debate over the U.S. involvement in Iraq turns violent; the tension between Harper and Guber over Marylin reaches the boiling point. |
| 4x04 - Chapter Seventy: |
| An enraged student slaps Marla's face in front of the class, and Marla slaps her back; Hanson discovers Allison behaves like a bully at school; Carmen asks Harper to remove Jake from her class. |
| 4x05 - Chapter Seventy-One: |
| An investment banker, convicted of securities fraud, avoids jail time by agreeing to community service: teaching math at Winslow High. A sexy and eccentric woman smashes into Guber's car and then crashes her way into his life. |
| 4x06 - Chapter Seventy-Two: |
| A student discovers Harper and Marilyn have been secretly dating and threatens to go to the school board; Hanson and Claire try to assist a student who is having trouble with his dad. |
| 4x07 - Chapter Seventy-Three: |
| Charlie Bixby (Dennis Miller) takes an unconventional approach when volunteering at a teen hotline; Marla decides to try in vitro fertilization and asks Harper to be the donor; Carmen reveals a secret from her past. |
| 4x08 - Chapter Seventy-Four: |
| Harper decides to call the FBI when he learns that a student has been accessing a terrorist recruitment web site from the school library; Ronnie learns that one of her students has HIV. |
| 4x09 - Chapter Seventy-Six: |
| Guber contends with a student who thinks he is Jesus and is using school funds to feed the homeless; Marla mistakenly books R.E.M. for a school fund-raiser. |
| 4x10 - Chapter Seventy-Five: |
| Guber discovers the high-school drum line's freshman hazing involves physical abuse; a student-produced TV documentary about Ronnie worries her; a father is sentenced to being handcuffed to his son for a week. |
| 4x11 - Chapter Seventy-Seven: |
| An overachieving student sues the school when she has to share presidency of the honor society with a black student in a wheelchair; Marlo begins her in-vitro process. |
| 4x12 - Chapter Seventy-Eight: |
| Views on affirmative action divide the students, and the teachers hope to quell the resulting tensions by debating the subject in front of the student body. Also, a new art teacher's anarchaic views rile Guber. |
| 4x13 - Chapter Seventy-Nine: |
| Henry gives bad advice to a brainiac student who wants to become an artist; Marla has a miscarriage; Rainy is thrown out of her foster home. |
| 4x14 - Chapter Eighty: |
| A former student of Winslow High dies in Iraq while serving the U.S. Army. Principal Harper receives a letter from the deceased student which brings back old memories back to the days when he took care of him and pulled him away from a life in the gutter. Danny Hanson struggles with a student in his class who's been hacking into the school's computer base; finding out about the teachers' private lives and upcoming tests. |
| 4x15 - Chapter Eighty-One: |
| Ronnie catches a male teacher hugging a female student; Hanson worries that he may be a control freak following an incident in his Drivers' Education class; several students are caught photographing themselves nude with only words written across their bodies. |