| Artist | Album | Song Title | Start/Stop | Scene |
| 5x01 - Rio: |
| Mogwai | Mr. Beast | | 00:40:08 - 00:41:26 (TV) | Ray Jr. holding Tiago Matos at gun point |
| Mogwai | Mr. Beast | | 00:43:04 - 00:43:31 (TV) | At the end of the episode |
| 5x02 - Going Under: |
| Boards Of Canada | The Campfire Headphase | | 00:01:34 - 00:02:44 (TV) | Calleigh processing the crime scene at the beginning |
| 5x03 - Death Pool 100: |
| Chingy | Hoodstar | | 00:00:36 - 00:01:45 (TV) | Second song at the party in the beginning |
| Death Cab for Cutie | Transatlanticism | | 00:39:41 - 00:43:39 (TV) | At the end of the episode |
| 5x04 - If Looks Could Kill: |
| Black Buddafly | Waist Deep OST | | 00:00:00 - 00:00:48 (TV) | At the beginning of the episode (feat. Fabolous) |
| Imogen Heap | Speak for Yourself | | 00:42:19 - 00:43:39 (TV) | At the end of the episode |
| 5x05 - Death Eminent: |
| SebastiAn | Ross Ross Ross EP | | 00:00:00 - 00:00:37 (TV) | At the beginning of the episode |
| Broadcast | The Future Crayon | | 00:37:29 - 00:38:06 (TV) | Ryan swabbing and testing the knife |
| 5x06 - Curse Of The Coffin: |
| DJ Cam | Dj Cam Revisited By ... | Success (Thievery Corporation Remix) | 00:27:22 - 00:27:46 (TV) | Valera working on axe swab |
| Chris Isaak | Forever Blue | | 00:41:24 - 00:42:19 (TV) | At the end of the episode |
| 5x07 - High Octane: |
| Ludacris | Release Therapy | | 00:00:00 - 00:01:04 (TV) | First song at the beginning of the episode |
| Turbonegro | Party Animals | | 00:01:04 - 00:01:55 (TV) | Second song at the beginning of the episode |
| Chamillionaire | The Sound of Revenge | | 00:38:04 - 00:38:38 (TV) | Luke getting busted at the end |
| 5x08 - Darkroom: *(Additional music info in episode details) |
| TV On The Radio | Return to Cookie Mountain | | 00:00:00 - 00:01:01 (TV) | At the beginning of the episode |
| Trabant | | The One (Filthy Dukes Remix) | 00:19:36 - 00:20:49 (TV) | At the photo shoot with all the women in bikinis |
| 5x09 - Going, Going, Gone: |
| Goldfrapp | Black Cherry | | 00:01:30 - 00:02:59 (TV) | The guy and the two girls in the bedroom at the beginning |
| 5x10 - Come As You Are: |
| Johnny Cash | American Recordings | | 00:41:07 - 00:43:46 (TV) | At the end of the episode |
| 5x11 - Backstabbers: |
| (None known) | | | | |
| 5x12 - Internal Affairs: |
| Eminem | Eminem Presents the Re-Up | | 00:00:00 - 00:00:51 (TV) | At the beginning of the episode (Eminem, 50 Cent, Cashis, & Lloyd Banks) |
| 5x13 - Throwing Heat: |
| (None known) | | | | |
| 5x14 - No Man's Land (1): |
| 2XL | Neighborhood Rapstar | | 00:00:00 - 00:01:07 (TV) | At the beginning of the episode |
| Friends From Rio | Friends From Rio 1 | | 00:05:09 - 00:05:35 (TV) | After the opening credits |
| 5x15 - Man Down (2): |
| Beck | Sea Change | | 00:03:41 - 00:05:24 (TV) | The team visting Eric in the hospital |
| Sol Seppy | The Bells of 1 2 | | 00:22:41 - 00:24:31 (TV) | Calleigh talking to Eric and Alexx |
| 5x16 - Broken Home: |
| Fredo Viola | The Sad Song EP | | 00:06:27 - 00:07:22 (TV) | Eric arriving at the crime scene |
| Alex Smoke | Paradolia | | 00:14:37 - 00:15:10 (TV) | Natalia testing for GHB |
| Marsmobil | Minx | | 00:30:53 - 00:31:35 (TV) | Lucille Clark's body getting exhumed |
| Paolo Nutini | These Streets | | 00:41:18 - 00:43:39 (TV) | At the end of the episode |
| 5x17 - A Grizzly Murder: |
| Kings Of Leon | Aha Shake Heartbreak | | 00:00:00 - 00:00:57 (TV) | At the beginning of the episode |
| k-os | Atlantis - Hymns for Disco | | 00:12:42 - 00:13:05 (TV) | Eric and Calleigh starting to process the hotel room |
| Juelz Santana | What the Game's Been Missing! | | 00:22:54 - 00:23:52 (TV) | Horatio and Frank visiting the club for the first time |
| Akon | Konvicted | | 00:30:17 - 00:31:37 (TV) | Horatio visiting the club for the second time |
| 5x18 - Triple Threat: |
| The Chemical Brothers | Surrender | | 00:00:00 - 00:01:57 (TV) | At the beginning of the episode |
| Erik Satie | Universal Sound Of Buddha-Bar | Gnossienne N° 1 (Buddha Bar Remix) | 00:41:08 - 00:43:13 (TV) | At the end of the episode |
| 5x19 - Bloodline: |
| k-os | Atlantis - Hymns for Disco | | 00:00:00 - 00:00:56 (TV) | At the beginning of the episode |
| Marsmobil | Minx | | 00:08:57 - 00:10:30 (TV) | Natalia processing Anna |
| Plus/Minus | Let's Build A Fire | | 00:42:22 - 00:43:40 (TV) | At the end of the episode |
| 5x20 - Rush: |
| Rick Ross | Port of Miami | | 00:04:01 - 00:04:15 (TV) | Right after the main credits |
| Amy Winehouse | Back to Black | | 00:10:29 - 00:10:54 (TV) | Heard when Horatio and Ryan go to the rehab facility for the first time |
| Sia | Colour the Small One | | 00:40:09 - 00:43:11 (TV) | At the end of the episode |
| 5x21 - Just Murdered: |
| Kings Of Leon | Aha Shake Heartbreak | | 00:00:00 - 00:01:43 (TV) | At the beginning of the episode |
| 5x22 - Burned: |
| P.J. Olsson | The Ironwood Sessions | | 00:09:57 - 00:10:18 (TV) | Valera working on skin from the teeth |
| 5x23 - Kill Switch: |
| Jim Jones | Hustler's P.O.M.E. (Product Of My Environment) | | 00:22:33 - 00:23:14 (TV) | Horatio going to see Tony Dekker |
| k-os | Atlantis - Hymns for Disco | | 00:24:57 - 00:25:14 (TV) | Right before Horatio talks to Cole for the second time |
| The Jealous Girlfriends | The Jealous Girlfriends | | 00:41:58 - 00:43:30 (TV) | At the end of the episode |
| 5x24 - Born to Kill: |
| Aqualung | Memory Man | | 00:40:11 - 00:43:40 (TV) | At the end of the episode |