| Plot |
| 5x01 - Nameless, Faceless: | | Hotch's unexplained absence quickly becomes apparent when the team is called back together to profile a killer who is targeting an emergency room doctor |
| 5x02 - Haunted: | | When a disturbed man kills several people at a pharmacy, the BAU must figure out what triggered his actions before he hurts anyone else |
| 5x03 - Reckoner: | | The BAU investigates a case in Rossi's hometown that involves both his personal and professional life |
| 5x04 - Hopeless: | | (No plot available) |
| 5x05 - Cradle to Grave: | | The team hunts a suspect who impregnates young women and has them give birth before murdering them |
| 5x06 - The Eyes Have It: | | The BAU team tracks a serial killer who keeps the eyes of his victims as souvenirs |
| 5x07 - The Performer: | | The BAU team follows a trail of murders that seems to align with the tour schedule of a rock star |
| 5x08 - Outfoxed: | | While tracking a family annihilator, the BAU must seek advice from "The Fox," one of the most horrific killers from the team's past who has an ominous message for Agent Hotchner |
| 5x09 - 100: | | The BAU team races to help Hotchner find The Reaper and save his family before it's too late |
| 5x10 - The Slave of Duty: | | While Agent Hotchner takes a leave of absence from the BAU, the team must regroup to solve a home invasion case |
| 5x11 - TBA: | | (No plot available) |
| 5x12 - TBA: | | (No plot available) |
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