| Artist | Album | Song Title | Start/Stop | Scene |
|---|
| 4x01 - A Change Is Gonna Come: |
| I'm From Barcelona | Let Me Introduce My Friends | | 00:00:29 - 00:02:14 (TV) | At the beginning of the episode. |
| Lily Allen | Alright, Still | | 00:17:29 - 00:19:32 (TV) | As Izzie decides to help save a deer. Meredith, Cristina, Izzie, Alex and George talk over a severed arm. Richard tries to talk to Miranda about her position. |
| Blonde Redhead | 23 | | 00:24:04 - 00:25:58 (TV) | The song plays while Izzie talks to George about her feelings. Mark and Derek talk about Meredith. |
| Meiko | Meiko | | 00:31:21 - 00:34:14 (TV) | The song plays as George and Lexie talk and admire the baby he delivered. |
| The Cinematic Orchestra | Ma Fleur | | 00:35:52 - 00:42:08 (TV) | At the end of the episode. |
| 4x02 - Love/Addiction: |
| Laura Izibor | | | 00:00:31 - 00:02:59 (TV) | At the beginning of the episode. |
| Trolle Siebenhaar | | | 00:13:29 - 00:14:27 (TV) | The song plays as Izzie talks George out of having a conversation with Callie. |
| Chris Garneau | Music for Tourists | | 00:21:45 - 00:23:42 (TV) | The song plays as George introduces himself to Mrs. Burke. The two have a heart to heart conversation about marriage. |
| The Rentals | The Last Little Life EP | Little Bit of You in Everything | 00:26:59 - 00:27:41 (TV) | This song plays as Meredith stitches up Alex in the clinic. Cristina tries to figure out why Mrs. Burke has stopped by for a visit. |
| Amy Obenski | Kite | | 00:34:59 - 00:36:15 (TV) | This song plays as Mrs. Burke finally talks with Cristina in the waiting room. |
| Gomez | | | 00:38:04 - 00:42:16 (TV) | At the end of the episode. |
| 4x03 - Let the Truth Sting: |
| Leslie Feist | The Reminder | | 00:00:24 - 00:02:08 (TV) | The song plays at the beginning of the episode. Izzie waits in front of the elevators. Alex overhears interns talking about George. |
| The Bravery | The Sun And The Moon | | 00:29:14 - 00:32:02 (TV) | The song plays as Izzie is informed that one of her patients has checked himself out of the hospital. Derek instructs Alex on how to conduct an emergency procedure. |
| The Perishers | Victorious | | 00:37:04 - 00:41:42 (TV) | The song plays as the episode comes to an end. Connie's friends come to visit her after the surgery, Meredith has a conversation with Lexie about her mother, and Alex tells some interns about George. |
| 4x04 - The Heart of the Matter: |
| Northern State | Can I Keep This Pen? | | 00:00:23 - 00:02:27 (TV) | At the beginning of the episode. |
| Prince Fatty | Milk And Honey EP | | 00:06:48 - 00:08:24 (TV) | Derek is checking an x-ray with Lexie and Cristina. Derek sends Cristina away. Meredith introduces Norman to Mark. Callie comes in to consult. |
| Kim Richey | Chinese Boxes | The Absence Of Your Company | 00:17:30 - 00:18:39 (TV) | Camille tells Richard, Adele, and Arlene that she is done fighting the cancer and wants to go home. |
| Yeah Yeah Yeahs | Is Is | | 00:22:30 - 00:23:40 (TV) | A lab tech asks George who he thinks will win between Callie and Izzie. George runs off. Izzie prepares to fight. Callie approaches Izzie in the cafeteria. |
| Meiko | Meiko | | 00:30:27 - 00:33:53 (TV) | Richard and Camille talk about her cancer. Richard agrees to send her home. Callie refuses Izzie's apology. |
| John Legend | | | 00:39:03 - 00:42:13 (TV) | At the end of the episode. |
| 4x05 - Haunt You Every Day: |
| The Gossip | Standing in the Way of Control | | 00:00:33 - 00:01:14 (TV) | The song plays at the beginning of the episode. Meredith walks down the hallway and enters the morgue. |
| Katie Herzig | Weightless | | 00:08:07 - 00:08:59 (TV) | The song plays as Norman tells Alex he isn't feeling well. Alex finds an unexpected visitor behind the curtain. |
| The Perishers | Victorious | | 00:10:37 - 00:11:53 (TV) | The song plays as Alex kisses an old friend in private. |
| The Bird & The Bee | Please Clap Your Hands | | 00:19:11 - 00:20:55 (TV) | The song plays as Meredith discusses with Cristina where to scatter her mother's ashes. George and Izzie join them for lunch. |
| The Perishers | Victorious | | 00:29:58 - 00:33:15 (TV) | The song plays as Alex rushes to find out what is happening with Norman. Lexie and George watch while Erica performs the heart surgery. Meredith and Lexie bond over their dead mothers. |
| Kendall Payne | Paper Skin | | 00:39:00 - 00:42:17 (TV) | The song plays at the end of the episode. |
| 4x06 - Kung Fu Fighting: |
| Imani Coppola | | | 00:00:32 - 00:01:56 (TV) | The song plays at the beginning of the episode. Callie sleeps on the sofa, as Cristina analyzes Meredith's feelings in a psychology book. |
| Miss Li | God Put a Rainbow in the Sky | | 00:17:16 - 00:19:01 (TV) | The song plays as George and Helena continue to hold the wedding dress. Alex and Callie attempt to pop Jackie's shoulder back into place. |
| Buddy | Alterations and Repairs | | 00:21:08 - 00:22:59 (TV) | Cristina presents an idea to Erica about how to perform the heart surgery. Erica recommends the risky surgery to Mr. Arnold. |
| New Buffalo | Somewhere, Anywhere | | 00:29:15 - 00:30:46 (TV) | The song plays as Helena tells George about her mother's financial difficulties. |
| The Magic Numbers | Those the Brokes | | 00:31:28 - 00:34:17 (TV) | The chief commends George for not buckling under pressure from Sloan. Erica begins the heart surgery on Mr. Arnold, Bailey and Meredith work on the skydiver, and Jackie awakes from her shoulder surgery. |
| Kate Nash | Made of Bricks | | 00:41:34 - 00:46:59 (TV) | At the end of the episode. |
| 4x07 - Physical Attraction... Chemical Reaction: |
| Derek Webb | The Ringing Bell | | 00:00:32 - 00:02:06 (TV) | At the beginning of the episode. |
| Northern State | Can I Keep This Pen? | | 00:19:35 - 00:20:00 (TV) | The song plays as Bailey walks in on Callie's surgery. Callie asks her to take care of her scheduling. |
| Joe Purdy | Take My Blanket And Go | | 00:35:30 - 00:37:29 (TV) | The song plays as Erica and Meredith test the success of the surgery. Richard talks to Callie about her problems with scheduling. Erica tells Sean the results of the surgery. |
| Calahan | | | 00:42:08 - 00:43:12 (TV) | The song plays in the bar as Lexie talks to the bartender and Mark tries to hit on Erica. |
| Priscilla Ahn | Priscilla Ahn EP | | 00:43:12 - 00:46:50 (TV) | At the end of the episode. |
| 4x08 - Forever Young: |
| Ben Lee | Ripe | | 00:00:00 - 00:02:22 (TV) | At the beginning of the episode. |
| Cary Brothers | Who You Are | | 00:13:57 - 00:17:10 (TV) | The song plays as Mark, Hahn, and the Chief sit in the cafeteria. Mark's ego gets injured by two high school girls. Cristina and Callie sit and gossip about Izzie and George, Tricia's fellow cheerleaders visit her in the hospital, and Marissa says goodbye to Danny before his surgery to remove the pencil. |
| Tegan and Sara | The Con | | 00:27:15 - 00:29:46 (TV) | The song plays as Izzie throws Emma and Janie out of Danny's room. Rose approaches Derek after the surgery, Callie tells Tricia that her injury could be a gift, and Hahn asks Cristina to get the entire CT scan. |
| Chris Garneau | Music for Tourists | | 00:32:01 - 00:36:58 (TV) | The song plays as Bailey visits Marcus after the surgery, but can't give him "the speech." Alex sees Lexie in the elevator and welcomes her to the club. Bailey vents to Derek in the waiting room. |
| Rilo Kiley | Under the Blacklight | | 00:39:42 - 00:41:42 (TV) | The song plays as the episode comes to an end. Derek and Mark go off to the bar. Sydney tells Derek what she brings to the table. Derek spots Rose as he leaves the bar. |
| 4x09 - Crash Into Me (1): |
| (None known) | | | | |
| 4x10 - Crash Into Me (2): |
| Santogold | Santogold | | 00:00:41 - 00:02:05 (TV) | At the beginning of the episode |
| Natalie Walker | Urban Angel | | 00:25:35 - 00:28:06 (TV) | The song plays as Meredith relays Ray's message to Stan's wife. Erica works on Jacob, Derek works on Mary, and Mark works on Nick. |
| Sara Melson | | | 00:38:05 - 00:42:15 (TV) | At the end of the episode. |
| 4x11 - Lay Your Hands On Me: |
| Katie Herzig | Weightless | | 00:00:28 - 00:01:50 (TV) | At the beginning of the episode. |
| Patty Griffin | Children Running Through | | 00:29:08 - 00:32:18 (TV) | The song plays as Bailey assures Tucker they will find time to baptize Baby Tuck. Izzie tells Alex she wants to have faith like Cristina. Richard tells Bailey that faith may not heal, but it can't hurt. |
| Lifehouse | Who We Are | | 00:33:43 - 00:35:48 (TV) | The song plays as Meredith and Derek part ways. Elizabeth tries her hand at healing baby Tuck, while Tucker and Bailey hold hands. The gang watches from a distance. |
| Joe Henry | | | 00:35:48 - 00:37:42 (TV) | The song plays as George explains himself to his mother. He tells her that he needs to take care of himself. |
| Caedmon's Call | | | 00:37:52 - 00:42:11 (TV) | At the end of the episode. |
| 4x12 - Where the Wild Things Are: |
| Lykke Li | Youth Novels | | 00:00:27 - 00:03:07 (TV) | At the beginning of the episode. |
| Goldfrapp | Seventh Tree | | 00:27:36 - 00:30:21 (TV) | Richard and Alex talk in surgery. George shows Derek Phillip's films. Scott goes into D.I.C. Phillip laughs when Richard tells him his brother is dead. Meredith tells Phillip and his wife about the tumor. |
| Greg Laswell | Dead Air EP | | 00:36:48 - 00:41:49 (TV) | At the end of the episode. |
| 4x13 - Piece of My Heart: |
| Katalyst | | | 00:00:00 - 00:00:54 (TV) | At the beginning of the episode. |
| Greenskeepers | | | 00:18:58 - 00:21:18 (TV) | The song plays as Lexie tells George that none of the interns want to play darts with Izzie. The Residents have lunch. Izzie attempts to fit in, the gang interrogates Alex about Rebecca, and Christina tries to talk "girl." |
| Neverending White Lights | | | 00:27:32 - 00:29:36 (TV) | The song plays as Phillip goes into his surgery. He tells Jennifer that he can't stand her being alone if he dies. Addison removes Nikki's baby. |
| Meaghan Smith | | | 00:32:05 - 00:34:26 (TV) | The song plays as the three surgeries take place. Erica works on the baby's heart, Derek injects the serum into Phillip's tumor, and Addison and Bailey work on Nikki. |
| The Republic Tigers | Keep Color | | 00:35:52 - 00:37:34 (TV) | The song plays as Bailey tells Addison that she can't talk about how she feels. Derek and Meredith decide to continue the clinical trials. Richard asks Addison to stay. |
| Jamie Lidell | Jim | | 00:38:42 - 00:42:15 (TV) | The song plays as the episode comes to an end. Callie dances with Mark, Erica sits with Addison, and the interns play darts at the bar. Izzie gets the test results of one of her patients. |
| 4x14 - The Becoming: *(Additional music info in episode details) |
| Beth Orton | The Other Side of Daybreak | Carmella (Four Tet Remix) | 00:00:00 - 00:01:28 (TV) | At the beginning of the episode. |
| Vampire Weekend | Vampire Weekend | | 00:17:26 - 00:18:49 (TV) | The song plays as George passes out the forms in the cafeteria. |
| Jay Clifford | | | 00:20:05 - 00:21:12 (TV) | The song plays as Alex has his temperature taken prior to Mrs. Marshall's surgery. Meredith wheels Darren into surgery and notices Todd still waiting in the hall. |
| The Submarines | Honeysuckle Weeks | | 00:25:33 - 00:27:50 (TV) | The song plays as Meredith tells Derek she can watch Darren on her own. Callie wants to have sex, but Mark is not in the mood. |
| Taken By Trees | Open Field | | 00:29:44 - 00:31:29 (TV) | The song plays as Meredith monitors Darren. Bailey passes Mark sitting pensively in the hallway, Todd demands an answer from Meredith and Darren's father, and Erica tells Mrs. Marshall that she's still at the top of the list for a new heart. |
| Frightened Rabbit | The Midnight Organ Fight | | 00:37:46 - 00:40:50 (TV) | The song plays as the episode comes to an end. |
| 4x15 - Losing My Mind: |
| The Puppini Sisters | The Rise & Fall of Ruby Woo | | 00:00:00 - 00:01:54 (TV) | At the beginning of the episode. |
| Alaska In Winter | Dance Party in the Balkans | Your Red Dress (Wedding Song At Cemetery) | 00:13:56 - 00:16:04 (TV) | The song plays as Lexie tries to talk to Meredith, but Cristina sends her away. Mark tells Callie he's a changed man. Richard argues with Erica about the Tapley surgery. |
| Electrocute | | | 00:18:47 - 00:19:53 (TV) | The song plays as Rebecca asks Mark for additional surgery, Meredith ambushes Dr. Wyatt in the ladies' room, and Lexie confronts Meredith in front of Dr. Wyatt. |
| The National | | | 00:25:32 - 00:27:30 (TV) | The song plays as Derek and Meredith wait for Andre's arrival with Greta. |
| Bon Iver | For Emma, Forever Ago | | 00:31:59 - 00:35:02 (TV) | The song plays as Tapley offers moral encouragement to George. Lexie gloats to Cristina about having observed the Tapley operation, George offers to watch Tuck for Bailey, and Alex gets some clothes from Izzie for Rebecca. |
| Joshua Radin | | Sky (featuring Ingrid Michaelson) | 00:37:24 - 00:40:36 (TV) | The song plays as the episode comes to an end. Meredith and Derek watch over Greta, Mark walks into the elevator and sees Callie and Erica, and Derek asks Rose to give him a second chance. |
| 4x16 - Freedom (1): |
| Coldplay | Viva La Vida | Death And All His Friends | 00:00:00 - 00:04:19 (TV) | At the beginning of the episode. |
| Duffy | Rockferry | | 00:06:00 - 00:08:32 (TV) | Bailey is trying to see the "bigger picture." Callie and Mark have sex in the on-call room. |
| The Rosewood Thieves | | | 00:22:39 - 00:25:00 (TV) | Richard has a conversation with Meredith. Dr. Wyatt and Meredith have a breakthrough conversation. Derek and Meredith agree to move up Jeremy and Beth's surgeries. Beth asks her mother about Jeremy. |
| Priscilla Ahn | Priscilla Ahn EP | | 00:29:30 - 00:31:10 (TV) | Alex helps Rebecca in the shower. Jeremy undresses and kisses Beth. Derek and Meredith discuss sex. Meredith distracts Beth's parents. |
| Ingrid Michaelson | | | 00:38:00 - 00:39:22 (TV) | Derek struggles to call time of death for Jeremy. Derek and Meredith enter Beth's room to tell her the news. Alex rushes to Rebecca's aid. Derek throws away the champagne. |
| 4x17 - Freedom (2): |
| Jon Foreman | Fall and Winter | | 00:07:32 - 00:09:42 (TV) | Meredith tells Dr. Wyatt that Dr. Ellis told her to be extraordinary. George is mad at Lexie for telling him about the intern test. Izzie tries to talk sense into Alex regarding Rebecca. |
| Adele | 19 | | 00:12:50 - 00:16:06 (TV) | Andrew begins to crash. Derek has an awkward conversation with Rose. Cristina begins a surgery. Richard sticks up for Cristina when Erica critizices her. |
| Bryn Christopher | My World | | 00:33:57 - 00:39:03 (TV) | Richard has a conversation with Meredith. Callie and Mark talk outside of the hospital. Calli and Erica have an interesting conversation. Derek looks for Meredith. Richard shows up to talk to Adele. There is a montage of the different characters kissing. |
| Ida Maria | | | 00:39:31 - 00:42:23 (TV) | At the end of the episode. |
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