| Artist | Album | Song Title | Start/Stop | Scene |
| 6x01 - Good Mourning: |
| Sweet Honey in the Rock | Selections 1976-1988 | | 00:00:00 - 00:01:41 (TV) | Everyone is trying to save george's life. Richard and Bailey are running a code on Izzie. |
| O+S | O+S | | 00:14:22 - 00:18:05 (TV) | Izzie and Callie decide which of George's organs will be available for transplant. Arizona needs Bailey's help. Derek and Meredith talk. Izzie says goodbye to George. |
| Joy Williams | | | 00:19:30 - 00:21:40 (TV) | Derek tells Richard about impending coup. Lexie tells Cristina that Joe and Jasmine left. Bailey questions transplant surgeons. |
| James Yuill | Turning Down Water for Air | | 00:21:40 - 00:22:48 (TV) | Cristina and Owen make out. Lexie sits with Clara who is frustrated. |
| Sweet Honey in the Rock | Selections 1976-1988 | | 00:39:09 - 00:42:17 (TV) | Mrs. O'Malley asks Owen a question. Lexie stops by Clara's room. Owen races to Clara's room. |
| 6x02 - Goodbye: |
| FanFarlo | | | 00:00:00 - 00:00:45 (TV) | Meredith notices Amanda sitting outside the hospital. Lexie is watching Clara sleep. . . |
| Katie Herzig | Apple Tree | | 00:16:38 - 00:17:32 (TV) | Lexie interrupts Meredith and Derek in the kitchen. |
| Lucy Schwartz | | | 00:27:19 - 00:29:41 (TV) | Derek and Arizona perform Andy's surgery. Derek lets Arizona make the cut. Owen tries to talk to Clara. |
| Emilíana Torrini | Fisherman's Woman | | 00:36:59 - 00:40:50 (TV) | Derek stops the elevator for Bailey. Owen is a little hesitant. Meredith loses her breath. Callie and Arizona laugh. |
| 6x03 - I Always Feel Like Somebody's Watchin' Me: |
| The Gossip | Music for Men | | 00:21:14 - 00:22:36 (TV) | Callie tells Arizona about other jobs. Alex worries about Izzie and interrupts Derek's surgery. |
| Ingrid Michaelson | Everybody | | 00:30:57 - 00:34:00 (TV) | Christina, Arizona and Sloan finish the operation. Tom & Jodie are being prepared for OP. |
| Rachael Yamagata | Elephants...Teeth Sinking Into Heart | | 00:36:26 - 00:38:33 (TV) | Meredith, Cristina, Izzie and Alex find out some news. Lexie checks her email. Megan and Olive find out news. Mark comforts Lexie. . . |
| Until June | Sound Of Defeat | | 00:39:05 - 00:42:14 (TV) | Callie and Arizona make an important decision about their relationship. Alex and Izzie talk. Baseball begins! |
| 6x04 - Tainted Obligation: |
| Voluntary Butler Scheme | Trading Things In | | 00:00:00 - 00:00:39 (TV) | Alex and Izzie are in a trailer in the woods. Alex experiences a series of unfortunate trailer incidents. A bear goes through their trash. Alex screams. |
| Dragonette | | | 00:15:37 - 00:16:32 (TV) | Alex and Cristina urge Meredith to donate her liver to Thatcher. Izzie finds a tick on Alex's neck. |
| Bachelorette | My Electric Family | | 00:24:16 - 00:26:23 (TV) | Owen and Izzie break the bad news to Randy. Izzie convinces Owen to try surgery again, beat the odds. Meredith is pissed. Alex urges her to ask Thatcher again. |
| Katie Herzig | Apple Tree | | 00:33:01 - 00:36:03 (TV) | Cristina and Derek comfort Meredith. Owen and Izzie open Randy's incision. Bailey begins surgery. Mark watches Cristina squirm during surgery. Derek watches Bailey perform a liver operation. Complications arise for Richard and Alex. Mark comforts Lexie. |
| Sébastien Schuller | Evenfall | | 00:38:47 - 00:42:17 (TV) | Cristina warns the Chief that he better not squander her talent. Izzie apologizes to Randy's wife. The chief gives Callie an Attending position. Izzie encounters the bear. Derek watches Meredith and Lexie sleep. Meredith and Lexie wake up and bond. |
| 6x05 - Invasion: |
| The Myrmidons | | | 00:00:00 - 00:01:26 (TV) | Cristina arrives to see a new sign and new people at Seattle Grace. Mercy West doctors crowd onto the elevator with Alex. Izzie defends George’s old cubby. Izzie, Alex and Cristina escape the crowds. |
| Traildriver | | | 00:20:05 - 00:21:42 (TV) | Billy steals April’s notebook and gives it to Lexie. The residents notice the Mercy Westers aren't doing lunch. |
| Greg Laswell | | | 00:38:20 - 00:41:09 (TV) | Richard has a big discussion with Izzie. Callie and her father reach an understanding. |
| 6x06 - I Saw What I Saw: |
| Metric | Fantasies | | 00:00:00 - 00:01:40 (TV) | Meredith has her IV removed. An orderly mops up blood. Alex paces and throws something. The doctors argue over a patient. |
| All Thieves | | | 00:03:37 - 00:06:19 (TV) | Cristina and Meredith talk about Mercy West surgeons. Cristina helps Owen with a burn victim. April confirms that she received the charts. |
| Faded Paper Figures | Dynamo | | 00:25:19 - 00:27:16 (TV) | Alex talks to Izzie's mom. Alex and Reed talk. Reed helps Charles with Cathy. Alex leaves Charles. |
| Jack Savoretti | Harder Than Easy | Songs From Different Times | 00:27:17 - 00:30:29 (TV) | Alex talks to Izzie and sees Charles struggling with Cathy. Reed and Jackson help. April gets her labs. Cathy is crashing hard. Alex, Jackson, and Reed work to save her. |
| Matt Hires | Take Us To The Start | | 00:38:22 - 00:42:16 (TV) | Derek talks to Richard. Alex throws his cell phone against the wall. The firefighters celebrate. Cristina chastises the doctors. |
| 6x07 - Give Peace a Chance: |
| Bat for Lashes | Two Suns | | 00:37:36 - 00:40:12 (TV) | Reed comforts Alex. Owen coaches Cristina. Richard and Derek have a conversation. |
| 6x08 - Invest In Love: |
| Metric | Fantasies | | 00:00:00 - 00:02:11 (TV) | Derek's pager goes off. Meredith hands it to him. Both Callie and Arizona's pages buzz. Half asleep, they get dressed. Callie and Arizona arrive at the hospital. Owen briefs Callie about a patient. Alex presents a pregnant car accident victim to Arizona. Callie and Arizona vie for the only prepped OR. |
| Bachelorette | My Electric Family | | 00:07:27 - 00:08:56 (TV) | Callie cooks a celebratory breakfast for Arizona, Mark, Lexie, Owen, and Cristina. |
| The Cinematic Orchestra | Ma Fleur | | 00:26:00 - 00:28:33 (TV) | Arizona carefully operates on Wallace, Charles assists. Arizona is on edge. Callie tries to help. Owen and Cristina burst in arguing. Arizona operates again on Wallace. She kicks Richard out of her OR. |
| Sébastien Schuller | Evenfall | | 00:30:47 - 00:33:14 (TV) | Reed talks to Jackson about Alex. Bailey thinks Alex would be good in PEDs. Cristina tells it straight to Hillary. Arizona oversees Richard breaking the news to Wallace's parents. Arizona approaches Callie's door and she gets a surprise. |
| Faded Paper Figures | Dynamo | | 00:33:54 - 00:34:44 (TV) | Callie apologizes and Arizona goes home. Jackson is drinking heavily. Lexie is bummed Arizona didn't like the party. |
| Brandi Carlile | Give Up the Ghost | | 00:35:10 - 00:38:27 (TV) | Jennings tries to save face with Wallace's parents. Alex still holds the baby, Reed joins him. A drunk Jackson has an awkward moment with Cristina. Alex returns the baby to a healthier Laura. Reed is smitten. |
| Correatown | | | 00:39:14 - 00:42:12 (TV) | Cristina has to talk with Owen. Arizona let Wallace's parents see him. Derek has an intimate moment with Meredith. Arizona and Callie say some important things to each other. |
| 6x09 - New History: |
| Joy Williams | | | 00:00:00 - 00:02:16 (TV) | Meredith runs into Izzie and Dr. Singer. Izzie wants Derek to treat Dr. Singer. Christina forgets the kiss from Jackson. Owen shares a surprise gift with Cristina and Jackson. |
| The Gossip | Music for Men | | 00:21:09 - 00:23:54 (TV) | Izzie asks Derek to operate pro bono. Derek agrees pending Richard's approval. Callie, Arizona, Mark, Owen, and Teddy discuss Cristina. Meredith, Cristina, and Alex talk about Teddy. Alex doesn't want to talk about Izzie. Mark, Callie, and Bailey talk about Richard. |
| Stars of Track and Field | A Time For Lions | | 00:29:50 - 00:32:27 (TV) | Arizona and Jackson watch as Teddy allows Cristina to troubleshoot. Alex and Izzie discuss what she did. |
| Greg Laswell | Covers | | 00:33:29 - 00:35:42 (TV) | Richard talks to Bailey. Izzie and Dr. Singer discuss Izzie's future. Cristina talks to Meredith about operating and Teddy. Bailey talks to Callie about Richard. Teddy confronts Owen. |
| The Civil Wars | | | 00:37:49 - 00:41:19 (TV) | Cristina thanks Owen for the gift. Meredith consoles Alex. Richards asks for another drink. Joe takes his car keys. Meredith is shocked to see Richard drinking. |
| 6x10 - Holidaze: |
| Sara Ramirez | | | 00:27:17 - 00:30:20 (TV) | During christmas dinner. |
| Coldplay | | Have Yourself a Merry Little Christmas | 00:30:20 - 00:32:06 (TV) | Richard tells Meredith that he gave up drinking. Sloan and Mark have a conversation. |
| Jars of Clay | Christmas Songs | | 00:32:49 - 00:36:35 (TV) | Owen tells Teddy that he needs to talk. Teddy and Owen talk. Cristina is excited about an organ donor. Teddy shows Cristina a patient. |
| Sébastien Schuller | Evenfall | | 00:36:35 - 00:38:40 (TV) | Mike asks Kelsey a question. Owen has a conversation with Cristina. |
| Ingrid Michaelson | | | 00:38:41 - 00:42:17 (TV) | Arizona, Derek, and Mark watch Corey. Bailey apologizes to her dad. Joe calls Meredith for help. |
| 6x11 - TBA: |
| (None known) | | | | |